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Modelling the dynamics of antibody production in birds

OLARTE, ANDRÉS and CLAVIJO, CARLOS and DÍAZ, HERNANDO (2011) Modelling the dynamics of antibody production in birds. Dyna; Vol. 78, núm. 166 (2011); 174-182 DYNA; Vol. 78, núm. 166 (2011); 174-182 2346-2183 0012-7353 .

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URL oficial: http://revistas.unal.edu.co/index.php/dyna/article...

Resumen

This paper presents a dynamical model of avian immune response, for antibody production purposes. Antibodies are fundamental tools for research, diagnosis, and the treatment of several diseases. It has been recognized for some time that antibodies obtained from poultry are an efficient alternative for applications in medicine and biology. Therefore, a dynamical model for this process might be very useful. The model being proposed consists of seven non-linear ordinary differential equations with constant coefficients that represent the main cellular and molecular populations in avian immune response. Values for the parameters were obtained from avian and mammalian literature. In silico-generated responses in terms of antibody concentrations are presented and compared to reported kinetics.

Tipo de documento:Artículo - Article
Información adicional:Derechos de autor reservados
Palabras clave:Avian immunology, antibodies, dynamical models.
Unidad administrativa:Revistas electrónicas UN > Dyna
Código ID:27835
Enviado por : Dirección Nacional de Bibliotecas STECNICO
Enviado el día :27 Junio 2014 19:02
Ultima modificación:18 Agosto 2014 18:08
Ultima modificación:18 Agosto 2014 18:08
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