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Cost-effectiveness analysis regarding postoperative administration of vitamin-d and calcium after thyroidectomy to prevent hypocalcaemia

Sanabria, Alvaro and Dominguez, Luis Carlos and Vega, Neil Valentin and Osorio, Camilo and Duarte, Daniel (2012) Cost-effectiveness analysis regarding postoperative administration of vitamin-d and calcium after thyroidectomy to prevent hypocalcaemia. Journal of Public Health; Vol. 13, núm. 5 (2011); 804-813 Revista de Salud Pública; Vol. 13, núm. 5 (2011); 804-813 0124-0064 .

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URL oficial: http://revistas.unal.edu.co/index.php/revsaludpubl...

Resumen

Objective Hypocalcaemia is a frequently arising complication following total thyroidectomy. Routine postoperative prophylactic administration of vitamin D or metabolites and calcium reduce the incidence of symptomatic hypocalcaemia; this article reports evaluating its cost-effectiveness in Colombia.Methods Meta-analysis was used for comparing the administration of vitamin D or metabolites to oral calcium or no treatment at all in patients following total thyroidectomy and a cost-effectiveness analysis was designed based on a decision-tree model with local costs.Results The OR value for the comparison between calcitriol and calcium compared to no treatment and to exclusive calcium treatment groups was 0.32 (0.13-0.79 95 %CI) and 0.31 (0.14-0.70 95 %CI), respectively. The most cost-effective strategy was vitamin D or metabolites and calcium administration, having a US $0.05 incremental costeffectiveness ratio.Conclusion Prophylactic treatment of hypocalcaemia with vitamin D or metabolites + calcium or calcium alone is a cost-effective strategy.

Tipo de documento:Artículo - Article
Palabras clave:Thyroid neoplasm, thyroidectomy, hypocalcaemia, cost-benefit
Unidad administrativa:Revistas electrónicas UN > Revista de Salud Pública
Código ID:23491
Enviado por : Dirección Nacional de Bibliotecas STECNICO
Enviado el día :27 Junio 2014 14:33
Ultima modificación:18 Agosto 2014 16:23
Ultima modificación:18 Agosto 2014 16:23
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